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Article

Further evidence of the involvement of the Wnt signaling pathway in Dupuytren’s disease

3 Dec 2015

Abstract excerpt

Genetic background plays an important role in the development of Dupuytren's disease. A genome-wide association study (GWAS) showed that nine loci are associated with the disease, six of which contain genes that are involved in Wnt signaling (WNT2, WNT4, WNT7B, RSPO2, SFRP4, SULF1). To obtain insight in the role of these genes, we performed expression studies on affected and unaffected patient's tissues....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26635199
DOI: 10.1007/s12079-015-0312-8

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