Article
A Dendritic Cell-Activating Rv1876 Protein Elicits Mycobacterium Bovis BCG-Prime Effect via Th1-Immune Response.
Biomolecules - 3 Sept 2021
Choi Seunga, Choi Han-Gyu, Back Yong Woo, Park Hye-Soo, Lee Kang-In, Gurmessa Sintayehu Kebede, Pham Thuy An, Kim Hwa-Jung
Abstract excerpt
The widely administered tuberculosis (TB) vaccine, Bacillus Calmette-Guerin (BCG), is the only licensed vaccine, but has highly variable efficiency against childhood and pulmonary TB. Therefore, the BCG prime-boost strategy is a rational solution for the development of new TB vaccines. Studies have shown that Mycobacterium tuberculosis (Mtb) culture filtrates contain proteins that have promising vaccine...
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