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Article

Identification of Novel Potential Vaccine Candidates against Tuberculosis Based on Reverse Vaccinology

1 Jan 2015

Abstract excerpt

Tuberculosis (TB) is a chronic infectious disease, considered as the second leading cause of death worldwide, caused by Mycobacterium tuberculosis. The limited efficacy of the bacillus Calmette-Guérin (BCG) vaccine against pulmonary TB and the emergence of multidrug-resistant TB warrants the need for more efficacious vaccines. Reverse vaccinology uses the entire proteome of a pathogen to select the best vaccine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25961021
DOI: 10.1155/2015/483150

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