Article

Early secretory antigen target of 6-kDa of Mycobacterium tuberculosis inhibits macrophage apoptosis and host defense via TLR2

2023-03-24

Abstract excerpt

Mycobacterium tuberculosis (M. tuberculosis) is an intracellular bacteria capable of evading the human immune system through various mechanisms. M. tuberculosis secretes many virulence factors when infecting host cells. The 6 kDa early secretory antigen target (ESAT-6) is one of the most virulent factors producted by the ESX-1 system, which acts alone or in conjunction with culture filtrate protein 10 (CFP-10) to...

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Literature Corpus work: 21806ebc-219a-52a0-84c9-d454dd64b5c0
DOI: 10.22541/au.167963771.11949216/v1

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