Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Instability Due to Spindle Anomalies Visualized in Mutants of Dictyostelium.

Cells - 29 Aug 2021

Ecke Mary, Prassler Jana, Gerisch Günther

Abstract excerpt

Aberrant centrosome activities in mutants of Dictyostelium discoideum result in anomalies of mitotic spindles that affect the reliability of chromosome segregation. Genetic instabilities caused by these deficiencies are tolerated in multinucleate cells, which can be produced by electric-pulse induced cell fusion as a source for aberrations in the mitotic apparatus of the mutant cells. Dual-color fluorescence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Segregation
Share to Dictyostelium
Share to Genomic Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microtubules

Share to Mitosis

Share to Mutation

Share to rac GTP-Binding Proteins

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 34571889
DOI: 10.3390/cells10092240
PMCID: PMC8469108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Instability Due to Spindle Anomalies Visualized in Mutants of Dictyostelium.PMID 34571889Read ↗

Regulated expression of the centrosomal protein DdCP224 affects microtubule dynamics and reveals mechanisms for the control of supernumerary centrosome number.Semantic proximity Read ↗

The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis in Dictyostelium cells.Semantic proximity Read ↗

Mitochondrial mutations impair signal transduction in Dictyostelium discoideum slugs.Semantic proximity Read ↗

Discoidin proteins of Dictyostelium are necessary for normal cytoskeletal organization and cellular morphology during aggregation.Semantic proximity Read ↗

Dictyostelium as a model for human lysosomal and trafficking diseases.Semantic proximity Read ↗

Differential effects of heterochromatin protein 1 isoforms on mitotic chromosome distribution and growth in Dictyostelium discoideum.Semantic proximity Read ↗

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant.Semantic proximity Read ↗

In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain.Semantic proximity Read ↗

The cluA- mutant of Dictyostelium identifies a novel class of proteins required for dispersion of mitochondria.Semantic proximity Read ↗

The actin cytoskeleton of Dictyostelium: a story told by mutants.Semantic proximity Read ↗

Cytoskeletal protein mutations and cell motility in Dictyostelium.Semantic proximity Read ↗

The monomeric clathrin assembly protein, AP180, regulates contractile vacuole size in Dictyostelium discoideum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.