In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain.

doi:10.1002/(SICI)1097-0169(1998)40:3<304::AID-CM8>3.0.CO;2-C

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Article

In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain.

Cell motility and the cytoskeleton - 1 Jan 1998

Pollock N, Koonce M P, de Hostos E L, Vale R D

Abstract excerpt

The transport of vesicular organelles along microtubules has been well documented in a variety of systems, but the molecular mechanisms underlying this process are not well understood. We have developed a method for preparing extracts from Dictyostelium discoideum which supports high levels of bi...

Topics

Animals
Biological Transport
Dictyostelium
Dyneins
Liposomes
Membranes
Microtubules
Molecular Weight
Mutation
Organelles

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