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Article

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant.

The Journal of cell biology - 1 Feb 1990

Fukui Y, De Lozanne A, Spudich J A

Abstract excerpt

To study the role of conventional myosin in nonmuscle cells, we determined the cytoskeletal organization and physiological responses of a Dictyostelium myosin-defective mutant. Dictyostelium hmm cells were created by insertional mutagenesis of the myosin heavy chain gene (De Lozanne, A., and J. A. Spudich. 1987. Science (Wash. DC). 236: 1086-1091). Western blot analysis using different mAbs confirms that hmm...

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Identifiers

PMID: 2404992
DOI: 10.1083/jcb.110.2.367
PMCID: PMC2116002

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