Article
Prostate cancer genomics, biology, and risk assessment through genome-wide association studies.
Cancer science - 1 Apr 2012
Nakagawa Hidewaki, Akamatsu Shusuke, Takata Ryo, Takahashi Atsushi, Kubo Michiaki, Nakamura Yusuke
Abstract excerpt
Prostate cancer (PC) is the most common malignancy observed in men. It is evident that genetic factors play some important roles in PC etiology. Recently, genome-wide association studies in diverse ethnic groups have identified more than 40 germline variants of various genes or chromosomal loci that are significantly associated with PC susceptibility, including multiple 8q24 loci, prostate-specific genes,...
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