Article
A Review of Prostate Cancer Genome-Wide Association Studies (GWAS).
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2018
Benafif Sarah, Kote-Jarai Zsofia, Eeles Rosalind A
Abstract excerpt
Prostate cancer is the most common cancer in men in Europe and the United States. The genetic heritability of prostate cancer is contributed to by both rarely occurring genetic variants with higher penetrance and moderate to commonly occurring variants conferring lower risks. The number of identified variants belonging to the latter category has increased dramatically in the last 10 years with the development of...
Topics
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Male
- Neoplasm Proteins
- Polymorphism, Single Nucleotide
- Prostatic Neoplasms