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Article

Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer’s disease

9 Jun 2021

Abstract excerpt

Background: Alzheimer's disease (AD) is an incurable and irreversible neurodegenerative disease, without a clear pathogenesis. Therefore, identification of candidates before amyloid-β plaque (Aβ) deposition proceeds is of major significance for earlier intervention in AD. Methods: To explore the potential noninvasive earlier biomarkers of AD in a 5XFAD mouse model, microRNAs (miRNAs) from urinary exosomes in...

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PMID: 34557649
DOI: 10.1002/ame2.12175

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