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Exosomal MicroRNAs modulate the cognitive function in fasudil treated APPswe/PSEN1dE9 transgenic (APP/PS1) mice model of Alzheimer's disease

2022-08-08

Abstract excerpt

Alzheimer’s disease (AD) is characterized by cognitive impairment caused by the accumulation of beta-amyloid (Aβ) plaques and trans-synaptic spread of tau pathology. Exosome has emerged as key mediators for neuronal development, maintenance, and cellular communication. However, the molecular mechanism of exosomal miRNAs related to AD remains unknown. In the present study, APPswe/PSEN1dE9 transgenic (APP/PS1) mice...

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Literature Corpus work
44167d73-c37b-5aab-b71f-964d7c868c20
DOI
10.21203/rs.3.rs-1895492/v1
Open publication

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Exosomal MicroRNAs modulate the cognitive function in fasudil treated APPswe/PSEN1dE9 transgenic (APP/PS1) mice model of Alzheimer's diseaseDOI 10.21203/rs.3.rs-1895492/v1
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