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MicroRNAs in tear fluids predict underlying molecular changes associated with Alzheimer’s disease

20 Mar 2023

Abstract excerpt

Extracellular circulating microRNAs (miRNAs) have been discussed as potential biomarkers for Alzheimer's disease (AD) diagnosis. As the retina is a part of the CNS, we hypothesize that miRNAs expression levels in the brain, particularly neocortex-hippocampus, eye tissues, and tear fluids are similar at different stages of AD progression. Ten miRNA candidates were systematically investigated in transgenic APP-PS1...

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PMID: 36941055
DOI: 10.26508/lsa.202201757

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