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MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease

20 May 2015

Abstract excerpt

The miRBase-21 database currently lists 1881 microRNA (miRNA) precursors and 2585 unique mature human miRNAs. Since their discovery, miRNAs have proved to present a new level of epigenetic post-transcriptional control of protein synthesis. Initial results point to a possible involvement of miRNA in Alzheimer's disease (AD). We applied OpenArray technology to profile the expression of 1178 unique miRNAs in...

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PMID: 25992776
DOI: 10.1371/journal.pone.0126423

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