Article
Influence of interleukin 17 A and 17 F polymorphisms in keratoconus.
Molecular biology reports - 1 Nov 2021
Gomes Isabela Bronchtein, Ayo Christiane Maria, Lopes Alessandro Garcia, Kumano Laurie Sayuri, de Faria Junior Geraldo Magela, de Almeida Gildásio Castello, Castiglioni Lilian, de Mattos Luiz Carlos, Brandão Cinara Cássia
Abstract excerpt
BACKGROUND: Until a few years ago, keratoconus was defined as a noninflammatory degenerative disease. However, recent studies have shown that the altered balance between inflammatory cytokines, proteases, and protease inhibitors, as well as free radicals and oxidants, have a crucial role in the pathogenesis of this disease. The aim of this study is to investigate whether interleukin 17 A G197A (rs2275913) and...
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