Article
Interleukin 17F Gene Polymorphism as a Potential Protective Factor in the Immunopathology of Ocular Toxoplasmosis.
Parasite immunology - 1 May 2024
da Silva Danilo Donizete, Frederico Fábio Batista, Previato Mariana, Siqueira Rubens Camargo, Bonini-Domingos Claudia Regina, de Souza Victor Hugo, Castiglioni Lilian, Brandão Cinara Cássia, de Mattos Luiz Carlos, Ayo Christiane Maria
Abstract excerpt
Ocular toxoplasmosis (OT) is characterised by intraocular inflammation due to Toxoplasma gondii infection. Studies have found that interleukin 17 (IL-17) plays a central role in the pathology of OT. However, nucleotide variability in IL17 and interleukin 17 receptor (IL17R) genes has not been characterised in OT. As cytokine gene polymorphisms may influence the expression of these molecules, the aim of this study...
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