Article
Interleukin 1 beta promoter polymorphism is associated with keratoconus in a Japanese population.
Molecular vision - 1 Jan 2013
Mikami Takenori, Meguro Akira, Teshigawara Takeshi, Takeuchi Masaki, Uemoto Riyo, Kawagoe Tatsukata, Nomura Eiichi, Asukata Yuri, Ishioka Misaki, Iwasaki Miki, Fukagawa Kazumi, Konomi Kenji, Shimazaki Jun, Nishida Teruo, Mizuki Nobuhisa
Abstract excerpt
PURPOSE: Polymorphisms in the interleukin 1 alpha (IL1A) and IL1B gene regions were previously associated with keratoconus in a Korean population. In the present study, we investigated whether the IL1A and IL1B polymorphisms are associated with keratoconus in a Japanese population. METHODS: A total of 169 Japanese patients with keratoconus and 390 Japanese healthy controls were recruited. We genotyped one IL1A...
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