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Article

IL1A and IL1B gene polymorphisms and keratoconus susceptibility: evidence from an updated meta-analysis.

Ophthalmic genetics - 1 Oct 2021

Harati-Sadegh Mahdiyeh, Sargazi Saman, Khorasani Milad, Ansari-Moghaddam Alireza, Mirinejad Shekoufeh, Sheervalilou Roghayeh, Saravani Ramin

Abstract excerpt

Background: Several single-nucleotide polymorphisms (SNPs) in IL1B genes have been associated with KTCN. However, the results of these studies were not conclusive. This meta-analysis association study is aimed to quantitatively estimate the association of IL1B rs16944 (g.4490T>C) and rs1143627 (g.4970C>T), and IL1A rs2071376 (c.615 + 169C>A) polymorphisms with KTCN susceptibility.Materials and Methods: Systematic...

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Identifiers

PMID: 33978542
DOI: 10.1080/13816810.2021.1925926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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