Article
Association of Lysyl oxidase (LOX) Polymorphisms with the Risk of Keratoconus in an Iranian Population.
Ophthalmic genetics - 1 Jan 2015
Hasanian-Langroudi Farzaneh, Saravani Ramin, Validad Mohammad-Hosein, Bahari Gholamreza, Yari Davood
Abstract excerpt
BACKGROUND: Keratoconus is a connective tissue-related eye disease with unknown etiology that causes the loss of visual acuity. Lysyl oxidase (LOX) is an amine oxidase that catalyzes the covalent cross-link of collagens and elastin in the extracellular environment, thus determining the mechanical properties of connective tissue. The current study aimed to investigate the possible associations between two LOX...
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