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Article

Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants.

BMC microbiology - 22 Sept 2021

Nair Harikrishnan A S, Subramoni Sujatha, Poh Wee Han, Hasnuddin Nabilah Taqiah Binte, Tay Martin, Givskov Michael, Tolker-Nielsen Tim, Kjelleberg Staffan, McDougald Diane, Rice Scott A

Abstract excerpt

BACKGROUND: Biofilms disperse in response to specific environmental cues, such as reduced oxygen concentration, changes in nutrient concentration and exposure to nitric oxide. Interestingly, biofilms do not completely disperse under these conditions, which is generally attributed to physiological heterogeneity of the biofilm. However, our results suggest that genetic heterogeneity also plays an important role in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34551714
DOI: 10.1186/s12866-021-02318-8
PMCID: PMC8459498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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