Article
Glucose starvation-induced dispersal of Pseudomonas aeruginosa biofilms is cAMP and energy dependent.
PloS one - 1 Jan 2012
Huynh Tran T, McDougald Diane, Klebensberger Janosch, Al Qarni Budoor, Barraud Nicolas, Rice Scott A, Kjelleberg Staffan, Schleheck David
Abstract excerpt
Carbon starvation has been shown to induce a massive dispersal event in biofilms of the opportunistic pathogen Pseudomonas aeruginosa; however, the molecular pathways controlling this dispersal response remain unknown. We quantified changes in the proteome of P. aeruginosa PAO1 biofilm and planktonic cells during glucose starvation by differential peptide-fingerprint mass-spectrometry (iTRAQ). In addition, we...
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