Article

<i>wspA</i> mutation mediated <i>Pseudomonas aeruginosa</i> rugose small colony variant and its hyper-biofilm

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Pseudomonas aeruginosa is a major multidrug-resistant pathogen whose biofilm formation complicates treatment. P. aeruginosa r ugose s mall c olony v ariants (RSCVs), characterized by enhanced biofilm production and resistance, pose significant clinical challenges. However, the formation mechanisms remain unclear in clinical strains. Paired clinical P. aeruginosa isolates AR8023-1 (wild-type...

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Literature Corpus work: c04f8401-24bf-56fb-9af8-d31a8ec4ab95
DOI: 10.1101/2025.09.15.676455

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