Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in surface-sensing receptor WspA lock the Wsp signal transduction system into a constitutively active state.

Environmental microbiology - 1 Mar 2022

Xu Anming, Wang Di, Wang Yunhao, Zhang Li, Xie Zhensheng, Cui Yifan, Bhamse Pramod, Yu Haiying, Zhang Xue-Xian, Li Defeng, Ma Luyan Z

Abstract excerpt

Pseudomonas aeruginosa rugose small-colony variants (RSCVs) are frequently isolated from chronic infections, yet, they are rarely reported in environmental isolates. Here, during the comparative genomic analysis of two P. aeruginosa strains isolated from crude oil, we discovered a spontaneous in-frame deletion, wspAΔ280-307 , which led to hyper-biofilm and RSCV phenotypes. WspA is a homologue of methyl-accepting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Biofilms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic GMP

Share to Gene Expression Regulation, Bacterial

Share to Mutation

Share to Pseudomonas aeruginosa

Share to Signal Transduction

Source

Identifiers

PMID: 34499799
DOI: 10.1111/1462-2920.15763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in surface-sensing receptor WspA lock the Wsp signal transduction system into a constitutively active state.PMID 34499799Read ↗

<i>wspA</i> mutation mediated <i>Pseudomonas aeruginosa</i> rugose small colony variant and its hyper-biofilmSemantic proximity Read ↗

Evolutionary divergence of the Wsp signal transduction system in β- and γ-proteobacteriaSemantic proximity Read ↗

The structure-function relationship of WspR, a Pseudomonas fluorescens response regulator with a GGDEF output domain.Semantic proximity Read ↗

<i>Pseudomonas aeruginosa</i> Rugose Small-Colony Variants Have Adaptations That Likely Promote Persistence in the Cystic Fibrosis LungSemantic proximity Read ↗

Effect of PEL exopolysaccharide on the wspF mutant phenotypes in Pseudomonas aeruginosa PA14.Semantic proximity Read ↗

A chemosensory system that regulates biofilm formation through modulation of cyclic diguanylate levels.Semantic proximity Read ↗

Pseudomonas aeruginosa Strains from Both Clinical and Environmental Origins Readily Adopt a Stable Small-Colony-Variant Phenotype Resulting from Single Mutations in c-di-GMP Pathways.Semantic proximity Read ↗

Constitutive production of c-di-GMP is associated with mutations in a variant of Pseudomonas aeruginosa with altered membrane composition.Semantic proximity Read ↗

<i>Pseudomonas aeruginosa</i> strains from both clinical and environmental origins readily adopt a stable small colony variant (SCV) phenotype resulting from single mutations in c-di-GMP pathwaysSemantic proximity Read ↗

Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments.Semantic proximity Read ↗

A three-component regulatory system regulates biofilm maturation and type III secretion in Pseudomonas aeruginosa.Semantic proximity Read ↗

Genetic diversification of Pseudomonas fluorescens maintained by multi-niche selection within biofilms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.