Article
Constitutive production of c-di-GMP is associated with mutations in a variant of Pseudomonas aeruginosa with altered membrane composition.
Science signaling - 14 Apr 2015
Blanka Andrea, Düvel Juliane, Dötsch Andreas, Klinkert Birgit, Abraham Wolf-Rainer, Kaever Volkhard, Ritter Christiane, Narberhaus Franz, Häussler Susanne
Abstract excerpt
Most bacteria can form multicellular communities called biofilms on biotic and abiotic surfaces. This multicellular response to surface contact correlates with an increased resistance to various adverse environmental conditions, including those encountered during infections of the human host and exposure to antimicrobial compounds. Biofilm formation occurs when freely swimming (planktonic) cells encounter a...
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