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Article

Association between NQO1 C609T polymorphism and bladder cancer susceptibility: a systemic review and meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Gong Min, Yi Qingtong, Wang Weiming

Abstract excerpt

There is growing evidence for the important roles of genetic factors in the host's susceptibility to bladder cancer. NAD(P)H:quinone oxidoreductase 1 (NQO1) is a cytosolic enzyme that catalyzes the two-electron reduction of quinoid compounds into hydroquinones. Since the NQO1 C609T polymorphism is linked to enzymatic activity of NQO1, it has also been hypothesized that NQO1 C609T polymorphism may affect the...

Topics

Case-Control Studies
Genetic Association Studies
Genetic Predisposition to Disease
Humans
NAD(P)H Dehydrogenase (Quinone)
Odds Ratio
Polymorphism, Single Nucleotide
Urinary Bladder Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23749485
DOI: 10.1007/s13277-013-0799-7

Genes

NQO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23749485-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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