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Article

NQO1, MPO, and the risk of lung cancer: a HuGE review.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2005

Kiyohara Chikako, Yoshimasu Kouichi, Takayama Koichi, Nakanishi Yoichi

Abstract excerpt

The aim of this study is to summarize the available molecular epidemiologic studies of lung cancer and metabolic genes, such as NAD(P)H quinone reductase 1 (NQO1) and myeloperoxidase (MPO). NQO1 plays a dual role in the detoxification and activation of procarcinogens whereas MPO has Phase I activity by converting lipophilic carcinogens into hydrophilic forms. Variant genotypes of both NQO1 Pro187 Ser and MPO...

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Share to NQO1 gene
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16170238
DOI: 10.1097/01.gim.0000177530.55043.c1

Genes

MPO
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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