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Article

NQO1, MPO, and the risk of lung cancer: a HuGE review.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2005

Kiyohara Chikako, Yoshimasu Kouichi, Takayama Koichi, Nakanishi Yoichi

Abstract excerpt

The aim of this study is to summarize the available molecular epidemiologic studies of lung cancer and metabolic genes, such as NAD(P)H quinone reductase 1 (NQO1) and myeloperoxidase (MPO). NQO1 plays a dual role in the detoxification and activation of procarcinogens whereas MPO has Phase I activ...

Topics

Genetic Predisposition to Disease
Granulocyte Colony-Stimulating Factor
Humans
Interleukin-3
Lung Neoplasms
NAD(P)H Dehydrogenase (Quinone)
Polymorphism, Genetic
Recombinant Fusion Proteins
Recombinant Proteins
Smoking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16170238
DOI: 10.1097/01.gim.0000177530.55043.c1

Genes

MPO
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16170238-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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