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Article

Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3.

European journal of endocrinology - 11 Oct 2021

Nolan James, Campbell Purdey J, Brown Suzanne J, Zhu Gu, Gordon Scott, Lim Ee Mun, Joseph John, Cross Simone M, Panicker Vijay, Medland Sarah E, Melton Phillip E, Beilin Lawrence J, Mori Trevor A, Mullin Benjamin H, Pennell Craig E, Wang Carol A, Dudbridge Frank, Walsh John P, Martin Nicholas G, Wilson Scott G

Abstract excerpt

OBJECTIVE: Genetic factors underpin the narrow intraindividual variability of thyroid function, although precise contributions of environmental vs genetic factors remain uncertain. We sought to clarify the heritability of thyroid function traits and thyroid peroxidase antibody (TPOAb) positivity and identify single nucleotide polymorphisms (SNPs) contributing to the trait variance. METHODS: Heritability of...

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Australia
Iodide Peroxidase
Thyroid Function Tests
Thyroid Gland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Triiodothyronine

Twins, Monozygotic

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PMID: 34524976
DOI: 10.1530/EJE-21-0614

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