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Article

Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies.

The Journal of clinical endocrinology and metabolism - 1 Mar 2020

Matana Antonela, Boutin Thibaud, Torlak Vesela, Brdar Dubravka, Gunjača Ivana, Kolčić Ivana, Boraska Perica Vesna, Punda Ante, Polašek Ozren, Barbalić Maja, Hayward Caroline, Zemunik Tatijana

Abstract excerpt

INTRODUCTION: Thyroid peroxidase (TPO) and thyroglobulin (Tg) are main components of the thyroid gland and play an essential role in thyroid hormone synthesis. The development of antibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) is the major diagnostic hallmark and early indicator of autoimmune thyroid disease. TPOAb and TgAb are under strong genetic influence; however, genetic factors that...

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PMID: 31794020
DOI: 10.1210/clinem/dgz239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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