Article

Identification of Ferroptosis-Related Gene Signatures Associated With Multiple Sclerosis Using Weighted Gene Co-expression Network Analysis

2021-02-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system leading to demyelination followed by neurological symptoms. Ferroptosis is a newly discovered pathogenic hallmark important for the progression of MS. However, the gene markers of ferroptosis in MS are still uncertain. <bold>Methods: </bold>In this study, mRNA expression profiles...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 08d92cf4-bfd8-5ea1-8e0c-b626129df3e5
DOI: 10.21203/rs.3.rs-218764/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of Ferroptosis-Related Gene Signatures Associated With Multiple Sclerosis Using Weighted Gene Co-expression Network AnalysisDOI 10.21203/rs.3.rs-218764/v1Read

Identification of ferroptosis-related gene signatures associated with multiple sclerosis using weighted gene co-expression network analysisSemantic proximity Read

Targeted RNAseq Revealed the Gene Expression Signature of Ferroptosis-Related Processes Associated with Disease Severity in Patients with Multiple SclerosisSemantic proximity Read

Unveiling the Molecular Landscape: Network Analysis of Genes, Proteins, and Transcription Factors in Primary Progressive and Secondary Progressive Multiple Sclerosis for Unraveling Disease Progression and Prognostic FactorsSemantic proximity Read

Identification of Potential Blood-based Biomarkers for Multiple SclerosisSemantic proximity Read

Finding Genetic Contributors to Parkinson’s Disease via Weighted Gene Co- expression Network AnalysisSemantic proximity Read

Role of ferroptosis in neuroimmunity and neurodegeneration in multiple sclerosis revealed by multi‐omics dataSemantic proximity Read

Integrated transcriptomics of multiple sclerosis peripheral blood mononuclear cells identified COPG1, RPN1, and KDM3B as potential biomarkersSemantic proximity Read

Immune gene network of neurological diseases: Multiple sclerosis (MS), Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD)Semantic proximity Read

Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysisSemantic proximity Read

In silico Analysis of Transcriptomic Profiling and Affected Biological pathways in Multiple SclerosisSemantic proximity Read

Identification and Functional Validation of ACSL1 as a Biomarker Regulating Ferroptosis in Nucleus Pulposus CellSemantic proximity Read

Identification and functional validation of ACSL1 as a biomarker regulating ferroptosis in nucleus pulposus cellSemantic proximity Read