A Deep Transcriptome Meta-Analysis Reveals Sex Differences in Multiple Sclerosis

Abstract excerpt

<title>Abstract</title><p><bold>Background:<italic/></bold>Multiple sclerosis (MS), a chronic auto-immune, inflammatory, and degenerative disease of the central nervous system, affects both males and females; however, females suffer from a higher risk of developing MS (2-3:1 ratio relative to males). The precise sex-based factors influencing risk of MS are currently unknown. Here, we explore the role of sex in MS...

Topics

Open a Topic to create a Post that cites this publication.

• Alternative Splicing
• Bioinformatics and Genomic Networks
• Gene Expression Profiling
• Gene Expression Regulation
• Multiple Sclerosis
• Polymorphism, Single Nucleotide
• RNA-Binding Proteins
• White Matter

Identifiers and source

Literature Corpus work

5be96ca7-0035-5331-b7e8-f129e4b107fb

DOI

10.21203/rs.3.rs-2011220/v1