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A deep transcriptome meta-analysis reveals sex differences in multiple sclerosis

5 Apr 2023

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS), a chronic auto-immune, inflammatory, and degenerative disease of the central nervous system, affects both males and females; however, females suffer from a higher risk of developing MS (2-3:1 ratio relative to males). The precise sex-based factors influencing risk of MS are currently unknown. Here, we explore the role of sex in MS to identify molecular mechanisms underlying...

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PMID: 37023829
DOI: 10.1016/j.nbd.2023.106113

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