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Targeted RNAseq Revealed the Gene Expression Signature of Ferroptosis-Related Processes Associated with Disease Severity in Patients with Multiple Sclerosis

5 Mar 2024

Abstract excerpt

Detrimental molecular processes in multiple sclerosis (MS) lead to the cellular accumulation of lipid peroxidation products and iron in the CNS, which represents the main driving force for ferroptosis. Ferroptosis is an iron-dependent form of regulated cell death, with proposed roles in neurodegeneration, oligodendrocyte loss and neuroinflammation in the pathogenesis of MS. Ferroptosis-related gene expression...

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Cancer-related molecular mechanisms research
Ferroptosis and cancer prognosis
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38474262
DOI: 10.3390/ijms25053016

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