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Article

Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets

1 Feb 2021

Abstract excerpt

Importance: Substantial genome-wide association study (GWAS) work in Parkinson disease (PD) has led to the discovery of an increasing number of loci shown reliably to be associated with increased risk of disease. Improved understanding of the underlying genes and mechanisms at these loci will be key to understanding the pathogenesis of PD. Objective: To investigate what genes and genomic processes underlie the...

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PMID: 33523105
DOI: 10.1001/jamaneurol.2020.5257

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