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Article

Multiplatform discovery and regulatory function analysis of structural variations in non-small cell lung carcinoma.

Cell reports - 7 Sept 2021

Xia Lin, Wang Zhoufeng, Wu Xinyue, Zeng Tianfu, Luo Wenxin, Hu Xinlei, Ni Yinyun, Che Guowei, Liu Lunxu, Zhang Wei, Xie Dan, Li Weimin

Abstract excerpt

Non-small cell lung carcinoma (NSCLC), the most common form of lung cancer, is the leading cause of cancer-related death worldwide. We perform whole-genome sequencing (WGS) on samples from 43 primary patients with NSCLC and matched normal samples and analyze their matched open chromatin data and transcriptome data. Our results indicate that next-generation sequencing (NGS) and the Bionano Genomics (BNG) platform...

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Identifiers

PMID: 34496260
DOI: 10.1016/j.celrep.2021.109660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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