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Article

Endogenous Bos taurus RECQL is predominantly monomeric and more active than oligomers.

Cell reports - 7 Sept 2021

Liu Na-Nv, Song Ze-Yu, Guo Hai-Lei, Yin Hu, Chen Wei-Fei, Dai Yang-Xue, Xin Ben-Ge, Ai Xia, Ji Lei, Wang Qing-Man, Hou Xi-Miao, Dou Shuo-Xing, Rety Stephane, Xi Xu-Guang

Abstract excerpt

There is broad consensus that RecQ family helicase is a high-order oligomer that dissociates into a dimer upon ATP binding. This conclusion is based mainly on studies of highly purified recombinant proteins, and the oligomeric states of RecQ helicases in living cells remain unknown. We show here that, in contrast to current models, monomeric RECQL helicase is more abundant than oligomer/dimer forms in living...

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Identifiers

PMID: 34496242
DOI: 10.1016/j.celrep.2021.109688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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