Article
Analyses of the functional regions of DEAD-box RNA "helicases" with deletion and chimera constructs tested in vivo and in vitro.
Journal of molecular biology - 21 Oct 2011
Banroques Josette, Cordin Olivier, Doère Monique, Linder Patrick, Tanner N Kyle
Abstract excerpt
The DEAD-box family of putative RNA helicases is composed of ubiquitous proteins that are found in nearly all organisms and that are involved in virtually all processes involving RNA. They are characterized by two tandemly linked, RecA-like domains that contain 11 conserved motifs and highly variable amino- and carboxy-terminal flanking sequences. For this reason, they are often considered to be modular...
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