Article
microRNA-4717 differentially interacts with its polymorphic target in the PD1 3' untranslated region: A mechanism for regulating PD-1 expression and function in HBV-associated liver diseases.
Oncotarget - 7 Aug 2015
Zhang Guoyu, Li Na, Li Zhu, Zhu Qianqian, Li Fang, Yang Cuiling, Han Qunying, Lv Yi, Zhou Zhihua, Liu Zhengwen
Abstract excerpt
Programmed cell death-1 (PD-1) is involved in hepatitis B virus (HBV) infection, the leading cause of hepatocellular carcinoma (HCC) worldwide. Single-nucleotide polymorphism, rs10204525, located in the PD1 3' untranslated regions (UTR), is associated with chronic HBV infection. MicroRNAs (miRNAs...
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