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Article

Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients.

Tumour virus research - 1 Dec 2022

Hassan Marwa, Attia Mohammed Saad, Ali-Eldin Zainab, El Attar Gamal, Elzallat Mohamed, Saad Hany Haroun Kaisar, Isaac Amira

Abstract excerpt

BACKGROUND: Considering the immune evasion role of programmed death-ligand 1 (PD-L1) in cancer development, its genomic variations might be closely associated with disease development and cancer risks. Accordingly, this study was performed to investigate how the PD-L1 gene polymorphisms affect the susceptibility to hepatitis C virus (HCV)-induced liver cirrhosis and cancer development in the Egyptian population....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36265835
DOI: 10.1016/j.tvr.2022.200249
PMCID: PMC9594630

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