Article
Genome-driven elucidation of phage-host interplay and impact of phage resistance evolution on bacterial fitness.
The ISME journal - 1 Feb 2022
Markwitz Pawel, Lood Cédric, Olszak Tomasz, van Noort Vera, Lavigne Rob, Drulis-Kawa Zuzanna
Abstract excerpt
When considering the interactions between bacteriophages and their host, the issue of phage-resistance emergence is a key element in understanding the ecological impact of phages on the bacterial population. It is also an essential parameter for the implementation of phage therapy to combat antibiotic-resistant pathogens. This study investigates the phenotypic and genetic responses of five Pseudomonas aeruginosa...
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