Article
Curcumin and Resveratrol Improve Muscle Function and Structure through Attenuation of Proteolytic Markers in Experimental Cancer-Induced Cachexia.
Molecules (Basel, Switzerland) - 13 Aug 2021
Penedo-Vázquez Antonio, Duran Xavier, Mateu Javier, López-Postigo Adrián, Barreiro Esther
Abstract excerpt
Muscle wasting and cachexia are prominent comorbidities in cancer. Treatment with polyphenolic compounds may partly revert muscle wasting. We hypothesized that treatment with curcumin or resveratrol in cancer cachectic mice may improve muscle phenotype and total body weight through attenuation of several proteolytic and signaling mechanisms in limb muscles. In gastrocnemius and soleus muscles of cancer cachectic...
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