Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer Cachexia Signaling Pathways Continue to Emerge Yet Much Still Points to the Proteasome

1 Mar 2007

Abstract excerpt

Cachexia is a life-threatening consequence of cancer that diminishes both quality of life and survival. It is a syndrome that is characterized by extreme weight loss resulting mainly from the depletion of skeletal muscle. Research from the past decades investigating the mechanisms of tumor-induced muscle wasting has identified several key cachectic factors that act through the ubiquitin-dependent proteasome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Muscle Physiology and Disorders
Share to Nutrition and Health in Aging
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17332276
DOI: 10.1158/1078-0432.ccr-06-2307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer Cachexia Signaling Pathways Continue to Emerge Yet Much Still Points to the ProteasomePMID 17332276Read ↗

Cancer-Associated Muscle Wasting—Candidate Mechanisms and Molecular PathwaysSemantic proximity Read ↗

Cancer cachexia is regulated by selective targeting of skeletal muscle gene productsSemantic proximity Read ↗

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasomeSemantic proximity Read ↗

Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networksSemantic proximity Read ↗

The Proteasome in Cancer Biology and TreatmentSemantic proximity Read ↗

The Pathway to Cancer Cachexia: MicroRNA-Regulated Networks in Muscle Wasting Based on Integrative Meta-AnalysisSemantic proximity Read ↗

Progressive development of melanoma-induced cachexia differentially impacts organ systems in miceSemantic proximity Read ↗

The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulationSemantic proximity Read ↗

The role of myostatin in muscle wasting: an overviewSemantic proximity Read ↗

MicroRNA-mRNA Co-sequencing Identifies Transcriptional and Post-transcriptional Regulatory Networks Underlying Muscle Wasting in Cancer CachexiaSemantic proximity Read ↗

Tumor-induced alterations in single-nucleus transcriptome of atrophying muscles indicate enhanced protein degradation and reduced oxidative metabolismSemantic proximity Read ↗

Cancer cachexia-induced muscle atrophy: evidence for alterations in microRNAs important for muscle sizeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.