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Article

Muscle Phenotype, Proteolysis, and Atrophy Signaling During Reloading in Mice: Effects of Curcumin on the Gastrocnemius.

Nutrients - 31 Jan 2020

Mañas-García Laura, Bargalló Nuria, Gea Joaquim, Barreiro Esther

Abstract excerpt

: We hypothesized that curcumin may mitigate muscle protein degradation and loss through attenuation of proteolytic activity in limb muscles of mice exposed to reloading (7dR) following immobilization (7dI). In gastrocnemius of mice (female C57BL/6J, 10 weeks) exposed to recovery following a seven-day period of hindlimb immobilization with/without curcumin treatment, markers of muscle proteolysis (systemic...

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Identifiers

PMID: 32024036
DOI: 10.3390/nu12020388
PMCID: PMC7071295

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