Article
CRISPR/Cas12a-Based Ultrasensitive and Rapid Detection of JAK2 V617F Somatic Mutation in Myeloproliferative Neoplasms.
Biosensors - 24 Jul 2021
Chen Miaomiao, Zhang Chunhua, Hu Zhiqing, Li Zhuo, Li Menglin, Wu Lingqian, Zhou Miaojin, Liang Desheng
Abstract excerpt
The JAK2 V617F mutation is a major diagnostic, therapeutic, and monitoring molecular target of Philadelphia-negative myeloproliferative neoplasms (MPNs). To date, numerous methods of detecting the JAK2 V617F mutation have been reported, but there is no gold-standard diagnostic method for clinical applications. Here, we developed and validated an efficient Clustered Regularly Interspaced Short Palindromic Repeats...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.