Article
Genetic diversity and expression profile of Plasmodium falciparum Pf34 gene supports its immunogenicity.
Current research in translational medicine - 1 Oct 2021
Krishna Sri, Bhandari Sneha, Vishwakarma Anup Kumar, Verma Anil Kumar, Singh Mrigendra P, Sharma Anjana, Singh Neeru, Bharti Praveen K
Abstract excerpt
PURPOSE OF THE STUDY: Genetic variation is one of the major obstacles in the development of effective vaccines. A multivalent malaria vaccine is required to increase efficacy and confer long term protection. In this context, we analysed the genetic diversity, expression profile, and immune response against Pf34. METHODS: Phylogenetic analysis was carried out using Pf34 orthologues sequences of various Plasmodium...
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