Article
Genetic and structural characterization of PvSERA4: potential implication as therapeutic target for Plasmodium vivax malaria.
Journal of biomolecular structure & dynamics - 1 Apr 2014
Rahul C N, Shiva Krishna K, Pawar Atul P, Bai Meera, Kumar Vijay, Phadke Sandhya, Rajesh Vidya
Abstract excerpt
Plasmodium vivax malaria is geographically the most widely distributed and prevalent form of human malaria. The development of drug resistance by the parasite to existing drugs necessitates higher focus to explore and identify new drug targets. Plasmodial proteases have key roles in parasite biology and are involved in nutritional uptake, egress from infected reticulocytes, and invasion of the new target...
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