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Article

Detecting causal relationship between metabolic traits and osteoporosis using multivariable Mendelian randomization.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Apr 2021

Zhang Q, Greenbaum J, Shen H, Zhao L-J, Zhang W-D, Sun C-Q, Deng H-W

Abstract excerpt

By adopting the extension approaches of Mendelian randomization, we successfully detected and prioritized the potential causal risk factors for BMD traits, which might provide us novel insights for treatment and intervention into bone-related complex traits and diseases. INTRODUCTION: Osteoporosis (OP) is a common metabolic skeletal disease characterized by reduced bone mineral density (BMD). The identified SNPs...

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Identifiers

PMID: 32970198
DOI: 10.1007/s00198-020-05640-5
PMCID: PMC7987914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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