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Article

The impact of bone mineral density on the risk of falling: evidence from genetic correlation and Mendelian randomization analysis.

Endocrine - 1 Oct 2024

Mao Rumeng, Peng Luyao, Zhang Youqian, Li Lin, Ren Yanrui

Abstract excerpt

BACKGROUND: Falls are the most common consequence of low bone mineral density (BMD). However, due to limitations inherent in observational studies, the causal relationship between the two remains unestablished. METHODS: This study utilized Mendelian Randomization (MR) analysis to explore the causal relationship between BMD and the risk of falling, incorporating linkage disequilibrium score (LDSC) regression for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38851644
DOI: 10.1007/s12020-024-03904-2

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