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Article

Immune cell β2-adrenergic receptors contribute to the development of heart failure.

American journal of physiology. Heart and circulatory physiology - 1 Oct 2021

Tanner Miles A, Maitz Charles A, Grisanti Laurel A

Abstract excerpt

β-Adrenergic receptors (βARs) regulate normal and pathophysiological heart function through their impact on contractility. βARs are also regulators of immune function where they play a unique role depending on the disease condition and immune cell type. Emerging evidence suggests an important role for the β2AR subtype in regulating remodeling in the pathological heart; however, the importance of these responses...

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Identifiers

PMID: 34415184
DOI: 10.1152/ajpheart.00243.2021
PMCID: PMC8816326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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