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Cardiac macrophages and their functions in homeostasis and injury.

Atherosclerosis - 1 Oct 2025

Trimaglio Giulia, Mirtschink Peter, El-Armouche Ali, Chavakis Triantafyllos

Abstract excerpt

Due to their remarkable plasticity, macrophages can adapt to diverse environments and challenges therein, thereby exerting tissue-specific and context-specific functions. Macrophages are the most frequent immune cell population present in the heart and contribute substantially to cardiac homeostasis and function. Moreover, macrophages are key regulators throughout all stages of heart injury, acquiring diverse...

Read the complete abstract on PubMed

Topics

Humans
Homeostasis
Macrophages
Animals
Myocardium
Phenotype
Heart Injuries

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Identifiers

PMID: 40913908
DOI: 10.1016/j.atherosclerosis.2025.120480

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