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Article

Blood DNA methylation profiles improve breast cancer prediction.

Molecular oncology - 1 Jan 2022

Kresovich Jacob K, Xu Zongli, O'Brien Katie M, Shi Min, Weinberg Clarice R, Sandler Dale P, Taylor Jack A

Abstract excerpt

Although blood DNA methylation (DNAm) profiles are reported to be associated with breast cancer incidence, they have not been widely used in breast cancer risk assessment. Among a breast cancer case-cohort of 2774 women (1551 cases) in the Sister Study, we used candidate CpGs and DNAm estimators of physiologic characteristics to derive a methylation-based breast cancer risk score, mBCRS. Overall, 19 CpGs and five...

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Source

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Identifiers

PMID: 34411412
DOI: 10.1002/1878-0261.13087
PMCID: PMC8732352

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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