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Article

Individual and joint performance of DNA methylation profiles, genetic risk score and environmental risk scores for predicting breast cancer risk.

Molecular oncology - 1 Jan 2020

Guan Zhong, Raut Janhavi R, Weigl Korbinian, Schöttker Ben, Holleczek Bernd, Zhang Yan, Brenner Hermann

Abstract excerpt

DNA methylation patterns in the blood, genetic risk scores (GRSs), and environmental risk factors can potentially improve breast cancer (BC) risk prediction. We assessed the individual and joint predictive performance of methylation, GRS, and environmental risk factors for BC incidence in a prospective cohort study. In a cohort of 5462 women aged 50-75 from Germany, 101 BC cases were identified during 14 years of...

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Identifiers

PMID: 31677238
DOI: 10.1002/1878-0261.12594
PMCID: PMC6944111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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